MedTrace Logo

Effect of Genetic Polymorphism on the Occurrence of Post-Operative Atrial Fibrillation After CABG

NCT03871647 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 256

Last updated 2021-11-09

No results posted yet for this study

Summary

Postoperative Atrial Fibrillation (POAF) is one of the most common complications following coronary artery bypass grafting (CABG) occurring to 20% - 40% of patients. It is associated with prolonged hospitalization, increased hospital costs, increased complications and mortality rate.

Despite the use of Beta Blockers, approximately 20% of patients develop atrial fibrillation following CABG surgery, suggesting a role for polymorphism in the genes The aim of the present study is to determine the minor allele frequency of some of the genes that affect the beta blockers' response and to determine the association between polymorphism in these genes and the occurrence of postoperative atrial fibrillation after coronary artery bypass grafting in Egyptian patients receiving perioperative beta blockers.

Conditions

Interventions

DRUG

Beta blocker

perioperative beta blockers

Sponsors & Collaborators

  • Misr International University

    collaborator OTHER

  • Ain Shams University

    lead OTHER

Principal Investigators

  • Dina M El Gindy, MSC · Misr Ineternational University

  • Lamiaa M ElWakeel, PhD · Ain Shams University

  • Mona F Schaalan, PhD · Misr International University

  • Ramy MR Khorshid, Md, PhD · Ain Shams Uiversity

  • Mohamed H Solayman, PhD · Ain Sham University

Eligibility

Min Age
18 Years
Max Age
100 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-03-11
Primary Completion
2020-12-07
Completion
2021-03-07

Countries

  • Egypt

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03871647 on ClinicalTrials.gov