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Gastric Emptying - Implications for the Pathogenesis of Type 2 Diabetes

NCT03864562 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 56

Last updated 2026-04-01

No results posted yet for this study

Summary

People of black African and Caribbean descent have a greater risk of developing type 2 diabetes than white Europeans. The aim of this study is to increase our knowledge of how the condition may arise, and what underlies this increased risk. Following a successful screening visit to confirm eligibility for the study, we will be investigating how quickly a glucose drink empties out of the stomach in 30 white Europeans and 30 people of black African or Caribbean descent. In addition, we will study the impact that gastric emptying rate has on blood glucose and satiety hormones released normally by the gut in response to eating. Blood and breath samples will be collected before and during an oral glucose tolerance test.

Conditions

  • Diabetes Mellitus, Type 2

Sponsors & Collaborators

  • University of Adelaide

    collaborator OTHER

  • University of Nottingham

    lead OTHER

Principal Investigators

  • Michael Horowitz, MD PhD · University of Adelaide

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-03-01
Primary Completion
2022-09-30
Completion
2023-03-31

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03864562 on ClinicalTrials.gov