MedTrace Logo

Hemodynamics During Induction of General Anesthesia After Prophylactic Ephedrine, Phenylephrine or Norepinephrine.

NCT03864094 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 128

Last updated 2024-10-04

No results posted yet for this study

Summary

In this trial the investigators want to examine if there is any difference in hemodynamic stability when giving equipotent prophylactic injections of ephedrine 0,1 mg/kg, phenylephrine 1 microg/kg, norepinephrine 0,1 microg/kg or sodium chloride (NaCl) 9 mg/ml during induction of general anesthesia with propofol and remifentanil.

Conditions

  • Hemodynamic Instability
  • Anesthesia, General
  • Anesthesia, Intravenous

Interventions

DRUG

Ephedrine

0,1 mg/kg

DRUG

Phenylephrine

1 microg/kg

DRUG

Norepinephrine

0,1 microg/kg

DRUG

Sodium chloride

0,1 ml/kg

DRUG

Propofol

2 mg/kg

DRUG

Remifentanil

1,7 microg/kg

Sponsors & Collaborators

  • Helse Fonna

    lead OTHER

Principal Investigators

  • Gunnar Sjøen, MD · Helse Fonna

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-03-15
Primary Completion
2023-12-14
Completion
2023-12-14

Countries

  • Norway

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03864094 on ClinicalTrials.gov