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Flow Cytometry Analysis of the Reactive Oxygen Species in Immature Granulocytes in Septic Patient

NCT03846596 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 34

Last updated 2020-04-08

No results posted yet for this study

Summary

Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to infection. Early during sepsis course, immature neutrophils could be found in the bloodstream and may be less efficient than mature neutrophils in reactive oxygen species (ROS) production. ROS induce an oxidative stress for bacteria which can protect through the SOS response. The main objective is to evaluate the level of ROS produced in the early steps of sepsis by the immature neutrophils.

Conditions

Interventions

BIOLOGICAL

Additional blood tube

Additional blood tube during care

Sponsors & Collaborators

  • University Hospital, Limoges

    lead OTHER

Principal Investigators

  • Thomas DAIX, MD · University Hospital, Limoges

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-03-26
Primary Completion
2020-03-10
Completion
2020-03-10

Countries

  • France

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03846596 on ClinicalTrials.gov