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Immune Homeostasis in Sepsis and Septic Shock

NCT04448951 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 200

Last updated 2024-08-21

No results posted yet for this study

Summary

Detailed description of immune response and its dynamics in sepsis and septic shock patiens by means of transcriptomics, flow-cytometry and cytokine analysis.

Conditions

  • Sepsis
  • Immunologic Paralysis
  • Immunologic Suppression
  • Immune Deficiency

Interventions

OTHER

transcriptomics

transcriptomics

OTHER

flow-cytometry

peripheral blood myeloid cells and lymphocytes flow-cytometry

OTHER

cytokines

peripheral blood cytokine analysis

Sponsors & Collaborators

  • Charles University, Czech Republic

    lead OTHER

Principal Investigators

  • Thomas Karvunidis, MD, PhD · Carles University Teaching Hospital and Faculty of Medicine in Pilsen, Pilsen, Czech Republic

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-09-01
Primary Completion
2025-08-31
Completion
2027-12-31

Countries

  • Czechia

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04448951 on ClinicalTrials.gov