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Mechanical Stimulation Improve the Fertilization in ICSI Cycle

NCT03810001 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 500

Last updated 2019-09-25

No results posted yet for this study

Summary

Most fertilization failures after ICSI are caused by failure of oocyte activation defects. But, to date, there is no effective method to overcome this obstacle. To investigate the effect of mechanical stimulation on fertilization failures, investigators plan to recruit women undergoing ICSI treatment cycles. The retrieved sibling oocytes from the patients were randomly divided into two groups. The control group conducted the standard ICSI procedure, while the experimental group conducted the modified ICSI procedure.Consequently, the fertilization rate, 2PN (two pronuclei) rate, 1PN rate, oocyte degradation rate,and exploitable embryos on D3 were recorded to evaluate ICSI cycle outcomes.

Conditions

  • Fertilization

Interventions

BEHAVIORAL

Mechanical Stimulation

micromanipulation technique before insertion of the microinjection needle into the oocyte and expulsion of the spermatozoon

Sponsors & Collaborators

  • Tang-Du Hospital

    lead OTHER

Principal Investigators

  • li bo · Reproductive Medicine Center, Tangdu Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
22 Years
Max Age
35 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-11-11
Primary Completion
2019-11-20
Completion
2019-12-25

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03810001 on ClinicalTrials.gov