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Characterization of Sperm Population Following Different Selection Procedures

NCT05383599 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 50

Last updated 2023-02-06

No results posted yet for this study

Summary

The present study aims to determine which of the sperm selection techniques used in IVF (In Vitro Fertilization) laboratory leads to selection of the best/healthiest sperm population based on their morpho-functional parameters. Different procedures are currently used in our laboratory to select the sperm population that will be used to inseminate the oocytes: Density Gradient Centrifugation (DGC), DGC in combination with Magnetic Activated Sperm Sorting (MACS), and Microfluidic Sperm Sorting (MSS). The sperm cells selected by these techniques will be evaluated for specific morpho-functional features such as, motility, morphological abnormalities, and apoptotic status \[phosphatidylserine translocation (early stages of apoptosis)\] and DNA (Deoxyribonucleic Acid) fragmentation as an indicator of stages of apoptosis.

Conditions

  • Male Infertility

Sponsors & Collaborators

  • Universitair Ziekenhuis Brussel

    lead OTHER

Principal Investigators

  • Neelke De Munck · Brussels IVF

Eligibility

Sex
MALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-07-16
Primary Completion
2023-01-16
Completion
2023-08-01

Countries

  • Belgium

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05383599 on ClinicalTrials.gov