Reducing High-Risk Geriatric Polypharmacy Via EHR Nudges: Pilot Phase
NCT03791580 · Status: WITHDRAWN · Phase: NA · Type: INTERVENTIONAL
Last updated 2025-12-19
Summary
Polypharmacy is common among older adults in the United States and is associated with harms such as adverse drug reactions and higher costs of care. This pilot-phase project is designed to test two electronic health record (EHR)-based behavioral economic nudges to help primary care clinicians reduce the rate of high-risk polypharmacy among their older adult patients.
Conditions
- Fall
- Congestive Heart Failure
- Chronic Kidney Failure
- Adverse Drug Event
Interventions
- BEHAVIORAL
-
Commitment nudge
The commitment nudge will ask clinicians to commit to discussing high-risk polypharmacy at the next office visit with patients who have high-risk polypharmacy. Clinicians who commit will receive a reminder just before the next office visit begins. The patient will also receive notification of the commitment via EHR patient portal. This nudge will be operationalized via two sequential clinician-facing EHR best practice alerts (BPAs): the first at time of opening any encounter (including encounters other than a face-to-face office visit, e.g., medication refills), and the second (contingent on making a commitment to discuss high-risk polypharmacy) at time of opening the subsequent encounter for a face-to-face office visit. Each of these BPAs will describe the specific high-risk polypharmacy criterion (or criteria) the patient meets, the specific harms associated with the medication(s) triggering the criterion/criteria, and lower-risk alternative treatment strategies.
- BEHAVIORAL
-
Justification nudge
The justification nudge will ask clinicians who prescribe or renew a drug that meets high-risk polypharmacy criteria (in the context of the patient's other medications) to write a brief justification for prescribing this high-risk medication. This written justification will be recorded in the patient's medical record. The best practice alert requesting the justification will also describe the specific high-risk polypharmacy criterion (or criteria) the patient meets, the specific harms associated with the medication(s) triggering the criterion/criteria, and lower-risk alternative treatment strategies.
Sponsors & Collaborators
- collaborator OTHER
-
University of California, Los Angeles
collaborator OTHER -
University of Southern California
collaborator OTHER -
University of Pittsburgh
collaborator OTHER -
National Institute on Aging (NIA)
collaborator NIH -
RAND
lead OTHER
Principal Investigators
-
Mark W Friedberg, MD, MPP · RAND
Study Design
- Allocation
- RANDOMIZED
- Purpose
- HEALTH_SERVICES_RESEARCH
- Masking
- NONE
- Model
- FACTORIAL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-02-01
- Primary Completion
- 2019-08-01
- Completion
- 2019-09-01
Countries
- United States
Study Locations
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