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Comparing HEPES-buffered With Bicarbonate-buffered as Handling Media During the ICSI Procedure on Live Birth Rate

NCT03778866 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 1057

Last updated 2019-08-07

No results posted yet for this study

Summary

The pH stability during human gamete handling for intracytoplasmic sperm injection (ICSI) is physiologically sound. As the pH change for bicarbonate-buffered medium, scientists assumed whether the use of HEPES or MOPS buffered medium would provide more stable pH, thereby better outcomes. However, the oil use and time frame outside the incubators have not been accounted for. This study is to evaluate the use of HEPES buffered medium compared with the bicarbonate-buffered medium on ICSI outcomes.

Conditions

Interventions

OTHER

Bicarbonate-buffered handling medium

The investigators will evaluate whether the usual bicarbonate culture medium can replace the HEPES buffered medium effectively.

Sponsors & Collaborators

  • Banoon IVF Center

    collaborator OTHER

  • Quena IVF Center

    collaborator UNKNOWN

  • Muhammad Fawzy

    lead OTHER_GOV

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-01-15
Primary Completion
2019-08-05
Completion
2019-08-05

Countries

  • Egypt

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03778866 on ClinicalTrials.gov