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Repeatability in Hyperpolarized 3-Helium With MRI

NCT03776747 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 18

Last updated 2023-11-01

Study results available
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Summary

The main purpose of this study is to assess and test the reproducibility and results of hyperpolarized 3-Helium gas as a contrast agent with Magnetic Resonance Imaging (MRI) of the lungs in healthy adult subjects.

Conditions

  • Radiation Exposure

Interventions

DRUG

Prone hyperpolarized 3 helium gas scan

Hyperpolarized gas used as a contrast agent to test reproducibility of MRI of the lungs/Images done while subject is prone.

DRUG

Supine hyperpolarized 3 helium gas scan

Hyperpolarized gas used as a contrast agent to test reproducibility of MRI of the lungs/Images done while subject is supine.

DIAGNOSTIC_TEST

Vitals

DIAGNOSTIC_TEST

Pulmonary Function Tests

Pre and post spirometry, diffuse lung carbon monoxide (DLCO), lung volumes

DIAGNOSTIC_TEST

Initial protocol MRI scan

Initial scan to determine placement

Sponsors & Collaborators

  • Eric A. Hoffman

    lead OTHER

Principal Investigators

  • Eric A Hoffman, PhD · University of Iowa

Study Design

Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2008-07-22
Primary Completion
2012-06-30
Completion
2012-06-30
FDA Drug
Yes

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03776747 on ClinicalTrials.gov