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Improving Human Cerebrovascular Function Using Acute Intermittent Hypoxia

NCT05164705 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 33

Last updated 2024-07-09

No results posted yet for this study

Summary

This study uses magnetic resonance imaging to determine whether 3 weeks of repeated exposure to Acute Intermittent Hypoxia can improve brain blood flow or blood flow regulation in healthy adults.

Conditions

  • Healthy Brain Perfusion

Interventions

OTHER

Acute Intermittent Hypoxia

Participants will wear a non-rebreathing face mask and alternate between breathing 9% O2 gas mixture for up to 1 minute, or until the target SpO2 of 85 percent is reached, and normal room air (21 percent O2) until 2 minutes are complete. This cycle will be repeated 15 times, resulting in a 30-minute protocol.

OTHER

Sham Acute Intermittent Hypoxia

Participants will wear a non-rebreathing face mask and breathe normal air (21 percent O2) for 30-minutes.

Sponsors & Collaborators

Principal Investigators

  • Molly G Bright, DPhil · Northwestern University

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
21 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-05-03
Primary Completion
2024-04-05
Completion
2024-04-05

Countries

  • United States

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05164705 on ClinicalTrials.gov