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MRI Study of Radiation-Induced Damage to White Matter and Blood-Brain-Barrier

NCT01988675 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 91

Last updated 2018-06-06

No results posted yet for this study

Summary

This is a study to determine if Magnetic Resonance Imaging (MRI) techniques can detect early changes in white matter (in the brain) and the blood-brain barrier resulting from radiation therapy.

Conditions

  • Brain Neoplasms

Interventions

RADIATION

Whole Brain Irradiation

RADIATION

Partial Brain Irradiation

BEHAVIORAL

Neuropsychological Testing

BEHAVIORAL

Quality of Life Questionnaire

DEVICE

Magnetic Resonance Imaging (MRI) Assessments

MRI Assessments include Diffusion Tensor Imaging (DTI)and Gd-DTPA (Diethylenetriamine Pentaacetic Acid - a radioactive tracer injected into the patient and viewed on images).

Sponsors & Collaborators

  • University of Michigan Rogel Cancer Center

    lead OTHER

Principal Investigators

  • Yue Cao, Ph.D. · University of Michigan

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2004-08-26
Primary Completion
2014-06-03
Completion
2014-06-03

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01988675 on ClinicalTrials.gov