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Commonly Used Medicines On Neonatal Units in the UK

NCT03773289 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 642729

Last updated 2021-04-28

No results posted yet for this study

Summary

This retrospective analysis of drug utilisation data aims to study the patterns of use of medicines in neonatal units in the UK from 2010 to 2017. Prescribing drugs in neonates can be complex and the application of pharmacotherapy principles can be challenging due to the lack of licenced formulations and limited evidence-base for indications, dosing and/or adverse events. A systematic review of drug utilisation pattern in neonatal units in different health care settings identified antibiotics, caffeine and vitamin supplements as the most commonly used drugs and highlighted that further research is needed to investigate drug utilisation and rational use of medicines in neonates. The only UK study included in this systematic review and available from our search of literature was conducted in 2009. This survey, however, had a low response rate (only 42% units responded) and it included data collection over a very short period of 2 weeks and that could limit its generalisability to other NICU settings. It identified the need for research in to medicines for neonates and that this research agenda should be informed by the extent of medication use in this field. However, our literature search revealed that there is very little information on the current patterns of medication use in neonates. An updated drug utilisation study is warranted in a neonatal setting in UK.

Conditions

  • Infant, Newborn
  • Pharmacoepidemiology
  • Intensive Care Units, Neonatal

Interventions

OTHER

No intervention

This is a retrospective, observational pharmacoepidemiological study using nationally collected data. There is no intervention.

Sponsors & Collaborators

  • University of Nottingham

    lead OTHER

Principal Investigators

  • Shalini Ojha, PhD · University of Nottingham

Eligibility

Min Age
0 Weeks
Max Age
6 Months
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-04-20
Primary Completion
2020-04-19
Completion
2021-04-19

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03773289 on ClinicalTrials.gov