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Cerebral Perfusion and Acute Respiratory Failure

NCT03733795 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 20

Last updated 2018-11-09

No results posted yet for this study

Summary

The most common reason for admitting babies and infants to an intensive care unit is due to respiratory distress (breathing difficulties). At present there are a number of different treatments for respiratory distress. These include drug treatments; non-invasive ventilation, where oxygen is given at high pressure to push it through the baby's lungs: ventilation where the baby is put on a breathing machine; or Extracorporeal Membrane Oxygenation (ECMO). This works by taking the blood from the body via a tube (usually) in the baby's neck, redirecting through a machine that oxygenates the blood, then returning it to the baby through another tube. Currently we know little about how different treatments have a different impact on brain perfusion (how much oxygen the brain gets). Using specialist, noninvasive ultrasound and doppler techniques, we are proposing to monitor the effect of these treatments on the brain.

Conditions

  • Cerebral Blood Flow and Neonates During Acute Respiratory Failure

Interventions

OTHER

TCD

Transcranial Doppler will be used to measure brain blood flow in the middle cerebral artery.

Sponsors & Collaborators

  • Alder Hey Children's NHS Foundation Trust

    collaborator OTHER

  • Liverpool John Moores University

    lead OTHER

Eligibility

Max Age
5 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-11-30
Primary Completion
2020-10-31
Completion
2020-10-31

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03733795 on ClinicalTrials.gov