Molecular and Cellular Characterization of Skull Base Tumors
NCT03759717 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 4000
Last updated 2025-09-22
Summary
The purpose of the study is to analyze biological samples and genetic material for basic science research investigating the molecular and cellular characterization of skull base tumors.
Conditions
- Skull Base Neoplasm
- Cellular Pathology
Interventions
- OTHER
-
Observation
Understanding the biology of skull base tumors will teach the investigators about the genesis and/or mechanisms of treatment resistance. The investigators hope to ultimately identify new targets which will add to the armamentarium by which to treat these tumors.
Sponsors & Collaborators
-
University of Pittsburgh
lead OTHER
Principal Investigators
-
Paul Gardner, MD · Associate Professor
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2018-10-03
- Primary Completion
- 2028-10-03
- Completion
- 2028-10-03
Countries
- United States
Study Locations
More Related Trials
-
A Pilot Study of Inpatient Hospice With Procurement of Brain Tumor Tissue on Expiration for Research Purposes
NCT01251913 ·Status: TERMINATED
-
Genetic and Molecular Characterization of Nervous System Lesions
NCT06314607 ·Status: RECRUITING
-
Study of Tissue Samples From Patients With Glioma or Other Brain Tumors
NCT00967200 ·Status: COMPLETED
-
Perfusion Magnetic Resonance Imaging in Measuring the Growth of Blood Vessels in Newly Diagnosed Brain Tumors
NCT00005790 ·Status: WITHDRAWN ·Phase: NA
-
Biomarkers for Prognosis of Glioblastoma (GBM)
NCT01493219 ·Status: COMPLETED
-
Characterization of Receptors in Non-functioning Pituitary Macroadenomas
NCT00852501 ·Status: UNKNOWN
-
Study of Stored Tumor Samples in Young Patients With Brain Tumors
NCT00897286 ·Status: TERMINATED
-
Laboratory Study of Early Tumor Markers in the Peripheral Blood of Glioblastoma Multiforme Patients
NCT01135875 ·Status: COMPLETED
-
Pituitary Tumor Surveillance: Pathogenic Correlation
NCT00599092 ·Status: RECRUITING
-
Skull Base and Low Grade Glioma Neurocognitive Magnetic Resonance Imaging (MRI) Study
NCT01212731 ·Status: COMPLETED
-
Surgical Resection of Latent Brain Tumors Prior to Recurrence
NCT04810871 ·Status: SUSPENDED ·Phase: NA
-
Natural History of and Specimen Banking for People With Tumors of the Central Nervous System
NCT02851706 ·Status: COMPLETED
-
Mapping Molecular Markers of Brain Tumour Activity Using MRI
NCT05140785 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Evaluation of Human Brain Tumor Therapy Response by Magnetic Resonance (MR)
NCT00724191 ·Status: COMPLETED
-
Oxygen-Enhanced MRI for Generating Hypoxia Maps in Patients With Intracranial Tumors
NCT05904704 ·Status: WITHDRAWN ·Phase: NA
-
Correlation Between the Genetic and Neuroimaging Signatures in Newly Diagnosed Glioblastoma Patients Before Surgery
NCT02590497 ·Status: WITHDRAWN ·Phase: NA
-
NovoTTF Treatment Signatures in Glioblastoma Patients at Autopsy
NCT03194971 ·Status: COMPLETED
-
Prospective Cohort of Patients With Newly Diagnosed Glioblastoma: Analysis of MMP2 and MMP9 Expression and Correlation to Neuro-imaging Features.
NCT03526822 ·Status: RECRUITING ·Phase: NA
-
Neuroblastoma Biology Study
NCT01587300 ·Status: RECRUITING
-
Study of Human Brain-Gut Axis and Gut Microbiome in Patients With Brain Lesions - Repository for Neuroscience Research
NCT06117930 ·Status: RECRUITING
-
A Family Study of Adults With Glioma
NCT00339352 ·Status: COMPLETED
-
MRI Mapping in Planning Radiation Therapy to the Base of Skull and Brain in Patients With Nonmetastatic Head and Neck Cancer
NCT00984074 ·Status: COMPLETED
-
DNA Analysis of Tumor Tissue Samples From Patients With Diffuse Brain Stem Glioma
NCT00899834 ·Status: COMPLETED
-
Imaging Biomarkers of Tissue Microstructure and Vasculature as Predictors of Glioblastoma Multiforme
NCT01604590 ·Status: COMPLETED
-
Establishment of a Brain and Spinal Tumor Tissue Bank
NCT00686387 ·Status: UNKNOWN