Detachable String Magnetically Controlled Capsule Endoscopy for Detecting High-risk Varices in Compensated Cirrhosis

Summary

Gastroesophageal varices is a serious complication of compensated advanced chronic liver disease (cACLD). Primary prophylaxis to reduce the risk of variceal haemorrhage is recommended if high-risk varices (HRV) are detected. We performed this study to compare the accuracy, patients' satisfaction and safety of detection of HRV by detachable string magnetically controlled capsule endoscopy (DS-MCCE) with esophagogastroduodenoscopy (EGD) as the standard.

Conditions

• Compensated Cirrhosis
• Gastroesophageal Varices Bleeding

Interventions

DIAGNOSTIC_TEST

Detachable string magnetically controlled capsule endoscopy

Esophagogastroduodenoscopy is performed 2 hours after the magnetically controlled capsule endoscopy (Ankon Medical Technologies Co. Ltd.).

Sponsors & Collaborators

• Beijing 302 Hospital

  collaborator OTHER

• Sir Run Run Shaw Hospital

  collaborator OTHER

• Zhujiang Hospital

  collaborator OTHER

• Shandong Provincial Hospital

  collaborator OTHER_GOV

• Shanghai Tongji Hospital, Tongji University School of Medicine

  collaborator OTHER

• Third Affiliated Hospital, Sun Yat-Sen University

  collaborator OTHER

• Guangdong Second Provincial General Hospital

  collaborator OTHER

• The Fifth Affiliated Hospital of Zunyi Medical College

  collaborator OTHER

• LanZhou University

  collaborator OTHER

• Sheffield Teaching Hospitals NHS Foundation Trust

  collaborator OTHER

• Changhai Hospital

  collaborator OTHER

• The Second Affiliated Hospital of Baotou Medical College

  collaborator OTHER

• Nanfang Hospital, Southern Medical University

  lead OTHER

Principal Investigators

• Xiaolong Qi, M.D. · LanZhou University

Eligibility

Min Age

18 Years

Max Age

75 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2018-11-09

Primary Completion

2019-12-03

Completion

2022-11-08

Countries

• China
• United Kingdom

Study Locations