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3D-MRE for Assessing Cirrhosis, Advanced Chronic Liver Disease and Portal Hypertension

NCT05475015 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 150

Last updated 2026-02-09

No results posted yet for this study

Summary

How to construct a novel, non-invasive, accurate, and convenient method to achieve prediction of hepatic venous pressure gradient (HVPG) is an important general problem in the management of portal hypertension in cirrhosis or advanced chronic liver disease. We plan to investigate the ability of three demensional-magnetic resonance elastography (3D-MRE) to establish a risk stratification system and perform tailored management for portal hypertension in cirrhosis or advanced chronic liver disease.

Conditions

  • Cirrhosis, Liver
  • Portal Hypertension
  • Advanced Chronic Liver Disease

Interventions

DEVICE

3D-MRE

All imaging studies were performed by using a 3.0-T MRI system ( GE Healthcare) with a phasedarray body coil.

DEVICE

HVPG

HVPG measurements are performed by well-trained interventional radiologists in accordance with standard operating procedures.

Sponsors & Collaborators

  • Zhongda Hospital

    collaborator OTHER

  • Shengjing Hospital

    lead OTHER

Principal Investigators

  • Yu Shi, Prof. · Shengjing Hospital

  • Shenghong Ju, Prof. · Zhongda Hospital

  • Xiaolong Qi, Prof. · Zhongda Hospital

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-08-16
Primary Completion
2026-07-01
Completion
2026-12-01

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05475015 on ClinicalTrials.gov