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Comparison of Human Papillomavirus Integrated DNA and Messenger RNA in Cervical Neoplasia

NCT02198365 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 250

Last updated 2014-07-23

No results posted yet for this study

Summary

The investigators hypothesis is HPV integration could result in expression of oncogene transcripts, and not only constitutive expression but also the level of expression will be decisive for transformation and the maintenance of the malignant phenotype. Moreover, the expression and level of HPV viral transcripts not HPV DNA viral loads is correlated to the severity in cervical intraepithelial neoplasia (CIN) and cervical carcinomas (CxCa).

Conditions

  • Cervical Intraepithelial Neoplasia

Sponsors & Collaborators

  • National Science and Technology Council, Taiwan

    collaborator OTHER_GOV

  • Cathay General Hospital

    lead OTHER

Principal Investigators

  • Chih-Ming Ho · Gynecologic Cancer Center, Cathay General Hospital

Eligibility

Min Age
20 Years
Max Age
80 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2007-01-31
Primary Completion
2009-01-31
Completion
2009-03-31

Countries

  • Taiwan

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02198365 on ClinicalTrials.gov