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Role of Copper-Albumin Complex in Treatment of Knee Osteoarthritis in Human

NCT03736109 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 60

Last updated 2019-01-10

No results posted yet for this study

Summary

Osteoarthritis (OA) is one of the most common forms of degenerative joint disease and a major cause of pain and disability affecting the aging population. It is a significant burden in terms of cost as well as the health of society and individuals. Here in our study we will try to evaluate a novel therapeutic method by using topical copper-albumin complexes cream in treatment of osteoarthritis. Then all the biochemical changes will be measured beside the evaluation of topical copper-albumin complexes cream effectiveness in relieving symptoms of the OA.

Conditions

  • Osteo Arthritis Knee

Interventions

GENETIC

Soluble and genetic biomarkers measurements

Insulin-Like Growth Factor-1 and Coll2-1 gene expression will be measured by real time PCR. In addition, syndecan 4, hyaluronic acid, substance P and nitric oxide will be measured in plasma by ELISA

Sponsors & Collaborators

  • Assiut University

    lead OTHER

Eligibility

Min Age
40 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-01-17
Primary Completion
2019-03-20
Completion
2019-03-30

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03736109 on ClinicalTrials.gov