IL-35+Breg/Il-35 Effect on T Cell Immune in Patients With CHB
NCT03734783 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 55
Last updated 2019-11-18
Summary
The investigators observed the level of IL-35 secreting B regulatory (IL-35+Bregs) cells in peripheral blood cells in patients with chronic hepatitis B, and analysed the relationship between the IL-35+Bregs level and disease stage, and Th1 and Th2 cells level.
Conditions
Sponsors & Collaborators
-
Changhai Hospital
lead OTHER
Eligibility
- Min Age
- 17 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2017-07-01
- Primary Completion
- 2019-11-15
- Completion
- 2019-11-15
Countries
- China
Study Locations
More Related Trials
-
Gene Discovery in CHB Patients to Identify Unknown Pathways That Lead to B and NK Cell Deregulation
NCT06853886 ·Status: RECRUITING ·Phase: NA
-
Observe Change of Endotoxaemia and Related Mediators in Patients With Chronic Hepatitis B Virus (HBV) Infection
NCT01107483 ·Status: COMPLETED
-
Immune Dynamics in the Natural History of Chronic HBV Infection
NCT07137247 ·Status: RECRUITING
-
Impact of Hepatitis B Immunoglobulins in Patients With Chronic Hepatitis B on Hepatocellular Carcinoma - a Proof of Concept Study
NCT05293158 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Impact of Hepatitis B Vaccination on HBs Antigenemia
NCT03193775 ·Status: COMPLETED ·Phase: NA
-
Sustained HBsAg and Viral Response in Patients Achieved HBsAg Loss by Interferon Treatment
NCT02336399 ·Status: UNKNOWN
-
Study on Gut Microbiota in Chronic HBV Infected Patients
NCT03587467 ·Status: UNKNOWN
-
HBsAg Declined Patients Follow-up Study
NCT05977283 ·Status: RECRUITING
-
Dynamic Changes of Monocytes and NK Cells of CHC Patient Treated by DAAs
NCT03063723 ·Status: COMPLETED
-
The Immunogenicity and Persistence of Booster Dose With Hepatitis B Vaccine in College Students
NCT05099757 ·Status: UNKNOWN ·Phase: PHASE4
-
Efficacy of Short-term Immunosuppressive Therapy and Anti-allergenic Therapy in Severe Acute Exacerbation of Chronic Hepatitis B
NCT01627236 ·Status: UNKNOWN ·Phase: NA
-
The Role and Regulatory Mechanism of Germinal Center Immune Response in Hepatitis B Virus Infection
NCT07240350 ·Status: RECRUITING
-
Evaluation of Chronic HBV Patients w/Evidence of HBV Replication and Normal or Minimally Elevated Liver Transaminases.
NCT00263614 ·Status: COMPLETED
-
Expression of Th9 Cells and Poor/Non-responsiveness to Hepatitis B Vaccination
NCT01441609 ·Status: UNKNOWN
-
HBsAb Response After HBV Vaccination in Chronic Hepatitis B Patients Who Have Lost HBsAg
NCT03405597 ·Status: UNKNOWN ·Phase: PHASE3
-
Immunogenicity of the Hepatitis B Vaccine
NCT04540653 ·Status: UNKNOWN ·Phase: PHASE4
-
Immune Response in Patients With Hepatitis B and C Infection
NCT02275221 ·Status: RECRUITING
-
Rapid T-cell Analysis Test in Patients With Chronic HBV and HBV/HDV Disease
NCT06372990 ·Status: RECRUITING
-
Risk of Hepatitis B Reactivation in Patients With Prior HBV Exposure Undergoing Rituximab-containing Chemotherapy: A Prospective Study
NCT01502397 ·Status: COMPLETED
-
Knowledge and Practice of Chinese Medical Specialists Regarding Chronic Hepatitis B Virus Infection
NCT02511743 ·Status: COMPLETED
-
Impact of Hepatitis B Virus on Inflammatory Bowel Disease
NCT06881238 ·Status: RECRUITING
-
Antigen-specific Immune Response to Hepatitis B Virus in Utero
NCT00845403 ·Status: UNKNOWN
-
Seroprevalence of Hepatitis B and Immune Response to Hepatitis B Vaccination in Chinese College Students
NCT01861613 ·Status: COMPLETED ·Phase: PHASE4
-
Pharmacogenomics Study on IL28B Genetic Variants in Chinese Children With Hepatitis C Virus Infection
NCT01607021 ·Status: UNKNOWN
-
Mechanism of DCs Dysfunction in Chronic HBV Infection
NCT03753308 ·Status: UNKNOWN