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Impact of Hepatitis B Virus on Inflammatory Bowel Disease

NCT06881238 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 162

Last updated 2025-03-18

No results posted yet for this study

Summary

The goal of this observational retrospective study is to assess the impact of hepatitis B virus (HBV) infection on the clinical course and outcomes of inflammatory bowel disease (IBD) in Egyptian patients.

Researchers will compare the IBD extent, location, severity, and behavior between IBD patients with and without HBV infection.

Participants will be subjected to history-taking (history of hospital admission and disease flare, surgical history, medication history, follow-up duration, and mortality), clinical examination, laboratory investigations, abdominal ultrasonography, and endoscopic examination.

Conditions

  • Inflammatory Bowel Disease (IBD)
  • Hepatitis B Virus

Interventions

OTHER

History of IBD course and outcome in HBV patients

Full history taking including: * Personal history (name, age, sex, occupation, residence, and marital state). * Complaint. * Age at diagnosis of IBD. * Medication history. * History of hospital admissions and disease flares. * Disease extent, location, and behavior. (Montreal classification, Truelove-Witts severity index). * Surgical history (intestinal resection in CD patients and total proctocolectomy in UC patients). * Follow up duration and mortality. * Data of endoscopic examination * Data of laboratory investigations (complete blood picture, HBV serology, liver and kidney function tests, erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP)).

Sponsors & Collaborators

  • Tanta University

    lead OTHER

Principal Investigators

  • Nabila A Elgazzar, MD · Tropical medicine and infectious diseases Department, Faculty of Medicine, Tanta University

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-12-01
Primary Completion
2025-05-30
Completion
2025-06-10

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06881238 on ClinicalTrials.gov