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Doxycycline in the Treatment of Aggressive Periodontitis

NCT03727620 · Status: COMPLETED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 24

Last updated 2018-11-01

No results posted yet for this study

Summary

The aim of the study was to compare the clinical effects of systemic use of doxycycline to amoxicillin plus metronidazole as adjunctive treatment in nonsurgical debridement of aggressive periodontitis (AgP). Twenty four patients with aggressive periodontitis were enrolled in this clinical study. They all received oral hygiene instruction and full-mouth nonsurgical debridement using manual instruments. The test group received as adjunctive antibiotic treatment 200 mg of doxycycline the first day followed by 100 mg per day during 14 days. The control group received 500 of amoxicillin and 250 of metronidazole, three times a day for 7 days.

Conditions

  • Aggressive Periodontitis

Interventions

DRUG

amoxicillin plus metronidazole

patients were administered 250 mg of Flagyl and 500 mg of Dyspamox, three times a day for 7 days

DRUG

Doxycycline

patients were administered 200 mg of Longamycine the first day and 100 mg per day for 14 days

Sponsors & Collaborators

  • Mohammed V Souissi University

    lead OTHER

Principal Investigators

  • Latifa BENRACHADI, Professor · Faculty of medicine dentistery, Mohammed V University of Rabat

Study Design

Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
16 Years
Max Age
36 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-01-06
Primary Completion
2014-06-06
Completion
2014-12-08

Countries

  • Morocco

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03727620 on ClinicalTrials.gov