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Locally Delivered Antibiotics for the Treatment of Periodontitis

NCT04125706 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 44

Last updated 2019-10-16

No results posted yet for this study

Summary

The sample consists of patients with moderate to severe periodontitis who will be subjected to machanical therapy in combination to local antibiotics. The participants will be divided into two groups, mechanical therapy with metronidazole hyclate, and mechanical therapy with minocycline hydrochloride. Both antibiotics will be delivered locally as gels. Outcome measures include probing pocket depth and several gingival indices. IL6 will be also measured for all participants.

Conditions

  • Periodontitis

Interventions

DRUG

Minocycline Topical

Minocycline will be delivered locally in the periodontal pocket

DRUG

Metronidazole Topical Gel

Metronidazole will be delivered locally in the periodontal pocket

Sponsors & Collaborators

  • Riyadh Elm University

    lead OTHER

Principal Investigators

  • Sasha M Suliman, MSc · Ar Riyad, Saudi Arabia, 11681

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
25 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-11-01
Primary Completion
2020-07-01
Completion
2020-09-01

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04125706 on ClinicalTrials.gov