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Evaluation of Neurotoxic Effect of Sevoflurane-Based AnaesthesiaGuided by Short-Term Olfactory Identification

NCT03726580 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 600

Last updated 2018-11-01

No results posted yet for this study

Summary

Nowadays there is increasing doubts about the safety of anesthesia . Anesthesiologists have to console the worried patients, who are anxious about the potential risks of anesthetic-induced brain damage, by suggesting that any detrimental effects would be "mild".Anesthetics are responsible for postoperative taste and odor defects and cognitive dysfunction.

Conditions

  • Neurotoxic Effect of Sevoflurane-Based Anaesthesia

Interventions

DRUG

Sevoflurane

Assess the effect of isoflurane, sevoflurane, propofol and regional anesthesia on the olfactory threshold, olfactory identification and endocrine regulation of associative memory in the postoperative period in old age group.

Sponsors & Collaborators

  • Amer Galal Younis,MD

    collaborator UNKNOWN

  • Tanta University

    lead OTHER

Principal Investigators

  • ahmed S Elgebaly, MD · Tanta University

Eligibility

Min Age
60 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-03-01
Primary Completion
2018-09-01
Completion
2018-10-01
FDA Drug
Yes

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03726580 on ClinicalTrials.gov