MedTrace Logo

Optimization of Desflurane in Elderly Patients

NCT01700907 · Status: COMPLETED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2014-11-27

Study results available
· View outcomes & findings →

Summary

Various issues had been pointed out when undergoing the anesthesia for elderly patients with sevoflurane, such as delayed emergence, post-operative trouble with swallowing.

Desflurane, which has a lower blood/gas partition coefficient, is expected to contribute the better emergence, along with the recent progress on optimization of delivered amount of anesthesia.

The purpose of this study is to compare the time to emergence in long elderly patient cases with desflurane or sevoflurane, with the recently developed drug-delivery optimization system "Aisys®" (GE Healthcare Japan).

Conditions

  • Postoperative Cognitive Dysfunction

Interventions

DRUG

Desflurane

The patients in this arm will be given the general anesthesia with desflurane and be used the Aysis as the anesthetic machine.

DRUG

Sevoflurane

The patients in this arm will be given the general anesthesia with sevoflurane and be used the Aysis as the anesthetic machine.

Sponsors & Collaborators

  • Sapporo Medical University

    lead OTHER

Principal Investigators

  • Michiaki Yamakage, M.D.,PhD · Sapporo Medical University, School of Medicine

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-08-31
Primary Completion
2013-02-28
Completion
2013-02-28

Countries

  • Japan

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01700907 on ClinicalTrials.gov