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The Ratio of Hypnotic to Analgesic Potency of Volatile Anesthetics

NCT03588429 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 90

Last updated 2024-04-09

No results posted yet for this study

Summary

The aim of this clinical trial is to evaluate the ratio of hypnotic to analgesic potency of sevoflurane and isoflurane at equi-minimum alveolar concentration using EEG analysis.

Conditions

  • Anesthesia

Interventions

DRUG

Sevoflurane

Anesthesia was maintained with sevoflurane in patients undergoing standardized nociceptive stimulus (long-lasting tetanic stimulus of the ulnar nerve; 30 s, 50 mA, 50 Hz, square-wave).

DRUG

Isoflurane

Anesthesia was maintained with isoflurane in patients undergoing standardized nociceptive stimulus (long-lasting tetanic stimulus of the ulnar nerve; 30 s, 50 mA, 50 Hz, square-wave).

Sponsors & Collaborators

  • Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine

    lead OTHER

Principal Investigators

  • Ruizhao Lv, M.D · Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
19 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-01-01
Primary Completion
2020-08-01
Completion
2020-12-01

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03588429 on ClinicalTrials.gov