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Circulating microRNAs as Novel Prognosis Biomarkers for Rheumatoid Arthritis

NCT03719469 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 150

Last updated 2018-10-26

No results posted yet for this study

Summary

The correlation of circulating serum miR-125ba and miR-146a expression and clinical response to green tea therapy were analysed in RA patients.Clinical response to green tea therapy for 24 weeks was calculated from DAS28 scores. Whereas , a decrease of 1.2 points or above in DAS28 scores at 24 weeks of treatment compared with baseline was defined as clinical response according to the EULAR response criteria.A ready-made solutions containing the primers and probes for human miR-146a and miR-125ba (Applied Biosystems, Foster City, CA) and real-time RT-PCR was estimated using an ABI 7300 system (Applied Bio systems).

Conditions

  • Rh Disease

Interventions

DIETARY_SUPPLEMENT

Green tea group

Sponsors & Collaborators

  • King Saud University

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-01-20
Primary Completion
2015-01-20
Completion
2015-09-20

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03719469 on ClinicalTrials.gov