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Tissue-specific Insulin Resistance in Obstructive Sleep Apnea: Role of Hypoxia

NCT03695315 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 48

Last updated 2026-02-13

No results posted yet for this study

Summary

Obstructive sleep apnea (OSA) is a common condition associated with significant adverse health outcomes. Our overarching hypothesis is that patients with OSA and hypoxia (H-OSA) have greater degrees of insulin resistance in both liver and adipose tissue when compared to those without hypoxia (NH-OSA) thus leading to increased risk for the development of diabetes in the former group.

Conditions

Interventions

DEVICE

Continuous Positive Airway Pressure

CPAP is a noninvasive treatment for sleep apnea

Sponsors & Collaborators

Principal Investigators

  • Jean-Marc Schwarz, PhD · University of California, San Francisco

  • Andrew Krystal, MD · University of California, San Francisco

Eligibility

Min Age
19 Years
Max Age
100 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-10-31
Primary Completion
2024-12-31
Completion
2024-12-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03695315 on ClinicalTrials.gov