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Genetics Of Autoimmunity In Type I Diabetes

NCT03648918 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 4000

Last updated 2026-03-16

No results posted yet for this study

Summary

The purpose of this study is to gain more information about the step-by-step process that causes someone to develop type 1 diabetes. Scientists think that a person's own immune system, directed by genetic and environmental factors play a major role in its development. Participation involves a blood draw, a brief medical history questionnaire and measurements of height and weight. Some participants will be asked to return for annual follow-up visits for 10 years.

Conditions

Interventions

OTHER

Blood Collection

Blood will be collected via venipuncture and analyzed. Blood samples will be analyzed for HLA haplotype (a genetic sequence related to type 1 diabetes susceptibility), plasma-induced signature, diabetes autoantibodies, complete blood count with differential, and serum and plasma for storage. For family members with diabetes, blood will also be tested for A1c.

Sponsors & Collaborators

  • Benaroya Research Institute

    collaborator OTHER

  • Indiana University

    collaborator OTHER

  • Medical College of Wisconsin

    lead OTHER

Principal Investigators

  • Martin Hessner, PhD · Medical College of Wisconsin

Eligibility

Min Age
2 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2001-08-31
Primary Completion
2050-01-31
Completion
2050-01-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03648918 on ClinicalTrials.gov