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Biomarkers of Heterogeneity in Type 1 Diabetes

NCT04977635 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 611

Last updated 2022-03-23

No results posted yet for this study

Summary

Biomarkers of heterogeneity in type 1 diabetes: establishment of a biobank and an integrated approach to clinical and metabolic phenotyping of individuals with established T1DM. In this project the investigators are searching for biomarkers in 600 patients with established (\>5 years) diabetes. The inter-relation and patterns of expression in clinical, (auto)immune, metabolic, inflammatory and other parameters, and (potential) biomarkers are investogated. Blood and urine samples are collected annually (over 3 years) in standardized conditions and biobanked. In addition, 150 patients will undergo additional metabolic testing (such as mixed meal-tests).

Conditions

Sponsors & Collaborators

  • University Medical Center Groningen

    collaborator OTHER

  • Diabeter Nederland BV

    lead OTHER

Principal Investigators

  • Henk-Jan Aanstoot, MD PhD · Diabeter Nederland BV

  • Bruce HR Wolffenbuttel, MD PhD · University Medical Center Groningen

  • Nel PH Geelhoed-Duijvestijn, MD PhD · Haaglanden Medical Center

Eligibility

Min Age
16 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-06-08
Primary Completion
2021-12-31
Completion
2021-12-31

Countries

  • Netherlands

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04977635 on ClinicalTrials.gov