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Unveiling Preclinical Idiopathic Macular Hole Formation

NCT02180633 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 200

Last updated 2016-06-17

No results posted yet for this study

Summary

A macular hole is a rupture in the macula. In terms of pathogenesis, as much as 80% are idiopathic (Idiopathic Macular Hole, IMH). The normal incidence of this condition is about 0.17%; however, there is a 10-29% chance of development of a macular hole in the fellow eye of patients suffering from unilateral macular hole.

Our hypothesis is that embedded in the topography of the retina is information that can allow for discrimination between healthy eyes and eyes with an increased risk of developing IMH. As such, our work aims to develop a system that allows the automatic identification of these eyes.

Conditions

  • Idiopathic Macular Hole

Interventions

OTHER

Optical Coherence Tomography Scan

As an observational study, the only interventive action taken is the acquisition of a non-invasive volumetric image of the retina via optical coherence tomography (OCT).

Sponsors & Collaborators

  • University of Coimbra

    lead OTHER

Principal Investigators

  • Rui Bernardes, Ph.D. · Institute for Biomedical Imaging and Life Sciences, Faculty of Medicine, University of Coimbra

Eligibility

Min Age
45 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2013-05-31
Primary Completion
2015-09-30
Completion
2015-09-30

Countries

  • Portugal

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02180633 on ClinicalTrials.gov