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Bioactive Compounds in Watermelon Modulating Oxidative Stress and Inflammation in Elders

NCT03626168 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 21

Last updated 2022-05-17

Study results available
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Summary

Watermelon is the only food with a unique combination of amino acids and antioxidants that may reduce artery stiffness. However, only 27% of older adults meet the daily recommendation for fruit intake. Because it tastes good and is convenient and easy to consume, watermelon juice is an innovative and impactful intervention to help elders easily meet recommendations for fruit servings. If effective, this intervention would be a simple, inexpensive way to combat cardiovascular diseases (CVD). Results will advance science by providing a better understanding whether four-week consumption of 100% watermelon juice may impact measures of vascular health and inflammation in postmenopausal women.

Conditions

Interventions

DIETARY_SUPPLEMENT

100% watermelon juice

Participants drank two 12-ounce servings of 100% watermelon juice per day for a four-week period.

OTHER

Placebo beverage

Participants drank two 12-ounce servings of a placebo beverage per day for a four-week period.

Sponsors & Collaborators

  • University of Alabama, Tuscaloosa

    lead OTHER

Principal Investigators

  • Amy C Ellis, PhD, RD · University of Alabama at Birmingham

  • Kristi Crowe-White, PhD, RD · University of Alabama at Birmingham

Study Design

Allocation
NON_RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
55 Years
Max Age
69 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-02-16
Primary Completion
2018-05-12
Completion
2018-05-12

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03626168 on ClinicalTrials.gov