MedTrace Logo

Dysbiosis and Immune Reconstitution After Allo-HSCT

NCT03616015 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 80

Last updated 2019-02-01

No results posted yet for this study

Summary

Preliminary (proof of concept), monocentric, interventional, prospective, non-randomized and analytic trial designed to simultaneously explore intestinal microbiota changes and early post-transplant immune reconstitution, and to correlate biological data with clinical data (antibiotics use, stress level, GVHD).

Conditions

  • Hematopoietic Stem Cell Transplantation

Interventions

BIOLOGICAL

blood samples

20 to 30 ml of blood sample (D0, D15, D30, D60, D90, D180, Y1, Y2)

BIOLOGICAL

fecal samples

1 g of feces (D-8, D0, D15, D30, D90)

BEHAVIORAL

Anxiety test

Test of Spielberger

BEHAVIORAL

Stress test

Test of Cohen

Sponsors & Collaborators

  • Central Hospital, Nancy, France

    lead OTHER

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-12-04
Primary Completion
2021-01-31
Completion
2022-09-01

Countries

  • France

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03616015 on ClinicalTrials.gov