Presepsin in the Diagnosis of Sepsis in Critically Ill Patients
NCT03584594 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 200
Last updated 2022-12-07
Summary
Sepsis is one of the most common causes of death worldwide. It is caused by a complex of inadequate host responses to infection. Sepsis remains a major challenge of modern intensive care medicine. Despite recent improvements, the incidence of sepsis in critically ill patients increases steadily (25%) and mortality rates remain unacceptably high (30%). It is difficult to distinguish the sepsis from the non-infectious systemic inflammatory response syndrome. Early identification of the origin of infection can help dramatically to improve outcome and reduce mortality. That is why clinicians need fast, reliable and specific biomarkers for sepsis recognition.
Conditions
Interventions
- DIAGNOSTIC_TEST
-
Presepsin measurement
Presepsin measurements are performed with PathFast immunoassay analytical system on the ICU, bedside method. (Mitsubishi Chemical, Japan).
Sponsors & Collaborators
-
Public Health Institute Ostrava
collaborator UNKNOWN -
University Hospital Ostrava
lead OTHER
Principal Investigators
-
Marcela Káňová, MD,Ph.D. · University Hospital Ostrava
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2018-06-01
- Primary Completion
- 2021-12-31
- Completion
- 2022-03-30
Countries
- Czechia
Study Locations
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