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Systemic Inflammatory Response: Thiamine and Magnesium Status (Sir TaM Study)

NCT03554668 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 47

Last updated 2020-04-28

No results posted yet for this study

Summary

We wish to determine to what extent magnesium, thiamine and transketolase activity are affected by the Systemic Inflammatory Response (SIR). The knee arthroplasty model affords the ideal study design, as surgery generates an inflammatory response.

Blood samples are drawn preoperatively and for up to four days post operatively, and again at three months post-operation.

Conditions

  • Inflammation
  • Magnesium Deficiency
  • Iron-deficiency
  • Thiamine Deficiency

Interventions

DIAGNOSTIC_TEST

Blood draw

We take blood samples at pre-op and subsequent time points, up to three months post op.

Sponsors & Collaborators

  • NHS Greater Glasgow and Clyde

    collaborator OTHER

  • Glasgow Royal Infirmary

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
99 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-01-15
Primary Completion
2019-06-01
Completion
2019-06-01

Countries

  • United Kingdom

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03554668 on ClinicalTrials.gov