MedTrace Logo

Prediabetes and Non Obstructive Coronary Atherosclerosis.

NCT03553030 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 172

Last updated 2018-06-12

No results posted yet for this study

Summary

Objectives: Prediabetes may condition an early endothelium dysfunction, and the development of non obstructive coronary stenosis (NOCS). Indeed, authors' study aim was to investigate the endothelial dysfunction, and Major Adverse Cardiac Events (MACE) in prediabetics vs. normo glycemic subjects.

Materials and Methods: 308 patients with evidence of left anterior descending (LAD) coronary NOCS (\<50% luminal stenosis), will entere prospectively into a database. After assessment of endothelial coronary dysfunction by acetilcoline infusion, 86 propensity score matched (PSM) prediabetics and 86 PSM normoglycemics will be consecutive enrolled in the study.

Conditions

Interventions

DEVICE

coronary artery angiography

In all patients authors performed a coronary artery angiography for detection of coronary artery stenosis.

Sponsors & Collaborators

  • University of Campania Luigi Vanvitelli

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-01-01
Primary Completion
2017-07-01
Completion
2018-01-01

Countries

  • Italy

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03553030 on ClinicalTrials.gov