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Magnetic Resonance Imaging in Obesity

NCT03528187 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 49

Last updated 2023-10-25

No results posted yet for this study

Summary

Obesity and its related conditions account for up to 5%of all health care spending in the UK and this is expected to double by 2030. Following weight loss, significant improvement in these obesity-related illnesses has been reported. However, there is limited understanding of how these improvements happen and in particular, little dedicated work has been done using imaging in the obese population to look at the effects of treatment.

Magnetic resonance imaging (MRI) is an imaging technique that allows assessment of fat concentration and volume without the use of ionising radiation. It is safe, non-invasive and well-tolerated by most patients.

There are several MRI imaging techniques that be can used for fat quantification. These include MR spectroscopy and Dixon methods with measurement of fat fraction. These techniques measure the fat in the body organs and also the fat in the abdomen and skin. Recent technical developments mean that the whole body can be scanned relatively quickly (typically 30-40 minutes).

Conditions

Interventions

OTHER

MRI

MRI scan (not involving ionising radiation) The MRI study will be conducted by a trained MR radiographer, supervised by the nominated researcher

OTHER

Written Consent

Student researcher or research nurses to take consent. Consent will be taken in the obesity clinic or radiology departments.

Sponsors & Collaborators

  • University College, London

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-05-31
Primary Completion
2021-12-06
Completion
2021-12-06

Countries

  • United Kingdom

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03528187 on ClinicalTrials.gov