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Research for Associated Genes for Gastric Cancer in Family Member With Affected First-Degree Relatives

NCT03486574 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 105

Last updated 2023-04-18

No results posted yet for this study

Summary

Familial gastric cancer accounts for 10% of all cases, but predisposing genetic variations is unknown except for CDH1 mutation.

Because Germline mutation is believed to be a key aspect of cancer predisposition, we plan to recruit persons with 2 or more affected family members in three-generation pedigree. The investigators will perform a whole-exome sequencing using DNA from blood samples of families including gastric cancer patients and non-gastric cancer patients

Conditions

Interventions

DIAGNOSTIC_TEST

Positive result from pathological test

Presence/absence of gastric cancer will be evaluated by upper gastroendoscopy or results of pathological test

Sponsors & Collaborators

  • Seoul National University Bundang Hospital

    lead OTHER

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-12-07
Primary Completion
2022-07-31
Completion
2022-12-31

Countries

  • South Korea

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03486574 on ClinicalTrials.gov