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The BLF Early COPD Development Partnership Grant

NCT03480347 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 1000

Last updated 2021-08-26

No results posted yet for this study

Summary

Most existing medical research has focused on patients with well-established COPD and poor lung function. Whilst this is important because such patients have lots of symptoms and problems, in some respects a better way of reducing health problems in the future would be to develop a strategy which focuses on patients with milder disease, and identifies which ones will go on to develop more severe problems and why these problems occur. The research in this application is designed to investigate these issues.

The main objective of the Partnership is to study the very early stages of the development of COPD. The investigators will do this by recruiting a novel cohort of smokers (age 30-45), in whom the investigators will follow the trajectories of lung function decline to identify prospectively those at risk of excess decline. This programme forms a unique UK consortium of 8 academic centres with excellent high quality publication records and broad experience in mechanistic, translational, clinical and epidemiological studies in COPD with key capabilities including primary care.

Conditions

Sponsors & Collaborators

  • Queen's University, Belfast

    collaborator OTHER

  • University of Southampton

    collaborator OTHER

  • University of Birmingham

    collaborator OTHER

  • University College, London

    collaborator OTHER

  • University of Nottingham

    collaborator OTHER

  • University of Edinburgh

    collaborator OTHER

  • University of Manchester

    collaborator OTHER

  • Nanyang Technological University

    collaborator OTHER

  • Imperial College London

    lead OTHER

Eligibility

Min Age
30 Years
Max Age
45 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-01-17
Primary Completion
2023-04-30
Completion
2023-04-30

Countries

  • United Kingdom

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03480347 on ClinicalTrials.gov