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Effect of THRIVE During Apneic Oxygenation in General Anesthesia on Biomarkers

NCT03453294 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2020-10-14

No results posted yet for this study

Summary

Oxygenation with high-flow nasal cannula with 100% oxygen have now been evaluated in a number of studies and the data are convincing. The THRIVE technique is able to oxygenate patients safely and vital parameters has been shown to be stable. But it is of great importance to evaluate this new concept regarding other potential negative physiological aspects such as biological stress response detected by blood-bourne biomarkers before implementing it into clinical practice.

Conditions

  • Anesthesia
  • Oxygen Toxicity

Interventions

DEVICE

Apnoeic oxygenation using THRIVE

Apnoeic oxygenation using THRIVE

DEVICE

Endotracheal intubation and mechanical ventilation

Endotracheal intubation and mechanical ventilation

Sponsors & Collaborators

  • Karolinska University Hospital

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-01-22
Primary Completion
2018-11-01
Completion
2018-11-01

Countries

  • Sweden

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03453294 on ClinicalTrials.gov