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Comparison of Physiological Effects of Two Types of High-Flow Oxygen Therapy in Tracheostomized Patients

NCT06816745 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2025-02-10

No results posted yet for this study

Summary

High-flow nasal oxygen therapy offers benefits like precise oxygen delivery, flow-related positive end-expiratory pressure generation and improved lung function. High-flow oxygen therapy can be applied via tracheostomy as high-flow tracheal oxygen. While high-flow tracheal oxygen has been used to facilitate weaning, it has diminished physiological effects due to bypassing upper airways. To enhance its effectiveness, researchers developed a modified high-flow tracheal oxygen tube with a smaller expiratory end diameter to increase airway resistance and pressure. This is a prospective randomized crossover study that aims to compare the physiological effects of standard and modified high-flow oxygen therapy in tracheostomized patients.

Conditions

  • Critical Care
  • Oxygen Therapy
  • Tracheostomy

Interventions

PROCEDURE

Modified high flow tracheal oxygen

Modified high-flow tracheal oxygen with flow rates of 40L/min and 60L/min will be performed.

PROCEDURE

Standard high flow tracheal oxygen

Standard high-flow tracheal oxygen with flow rates of 40 L/min and 60 L/min will be performed.

Sponsors & Collaborators

  • Jian-Xin Zhou

    lead OTHER

Principal Investigators

  • Jian-Xin Zhou, MD, PhD · Capital Medical University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-02-20
Primary Completion
2025-11-30
Completion
2025-12-30

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06816745 on ClinicalTrials.gov