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The Effect of Hyperoxia on Ventilation During Recovery From General Anesthesia

NCT05379673 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2025-05-16

No results posted yet for this study

Summary

In this randomized-controlled trial the investigators will examine the effect of oxygen supplementation on the recovery of breathing for 90 minutes in the immediate post-anesthesia period starting from extubation of the trachea.

Conditions

  • Ventilatory Depression
  • Postoperative Respiratory Failure

Interventions

OTHER

Oxygen Gas for Inhalation

Oxyhemoglobin saturation (SpO2) higher than 96% vs SpO2 between 90% and 94%.

Sponsors & Collaborators

Principal Investigators

  • Anthony Doufas, MD, PhD · Professor, Department of Anesthesiology, Stanford University Medical School

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-10-04
Primary Completion
2026-07-31
Completion
2026-12-31

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05379673 on ClinicalTrials.gov