MedTrace Logo

SOD1 Kinetics Measurements in ALS Patients

NCT03449212 · Status: SUSPENDED · Type: OBSERVATIONAL · Enrollment: 86

Last updated 2024-07-25

No results posted yet for this study

Summary

Washington University in St. Louis is seeking participants with ALS for a study to determine the half-life of the protein SOD1 in the cerebral spinal fluid. Mutations in the SOD1 gene are known to cause some forms of familial ALS. Researchers are developing a treatment to reduce the level of SOD1 in familial ALS, but need to know more about how long SOD1 stays in the body ("half-life") to help determine if the new treatment is effective.

Conditions

  • Amyotrophic Lateral Sclerosis, Familial
  • Amyotrophic Lateral Sclerosis, Sporadic

Sponsors & Collaborators

  • Massachusetts General Hospital

    collaborator OTHER

  • Washington University School of Medicine

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2012-12-31
Primary Completion
2025-12-31
Completion
2026-12-31

Countries

  • United States

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03449212 on ClinicalTrials.gov