ALS Research Collaborative
NCT06885918 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 2000
Last updated 2025-03-20
Summary
The goal of this natural history study is to learn more about the biological and clinical aspects of amyotrophic lateral sclerosis (ALS). This study's findings will help with drug discovery, biomarker discovery, and outcome measure validation. Adults living with ALS, other motor neuron diseases (MND), a known mutation related to ALS and healthy volunteers contribute prospective and retrospective data to this study remotely. The study is sponsored and conducted by the ALS Therapy Development Institute.
Conditions
- Amyotrophic Lateral Sclerosis
- ALS (Amyotrophic Lateral Sclerosis)
- ALS With Frontotemporal Dementia (ALS/FTD)
- Motor Neuron Disease
- Motor Neuron Disease, Amyotrophic Lateral Sclerosis
Sponsors & Collaborators
-
ALS Therapy Development Institute
lead OTHER
Principal Investigators
-
Fernando G Vieira, M.D. · ALS Therapy Development Institute
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2014-09-12
- Primary Completion
- 2035-01-31
- Completion
- 2035-01-31
Countries
- United States
Study Locations
More Related Trials
-
Target ALS Biomarker Study; Longitudinal Biofluids, Clinical Measures, and At Home Measures
NCT05137665 ·Status: RECRUITING
-
Biomarker-driven Phenotypic Dissection of Amyotrophic Lateral Sclerosis
NCT06318598 ·Status: RECRUITING
-
Genomic Translation for Amyotrophic Lateral Sclerosis Care
NCT02795897 ·Status: COMPLETED
-
Determining the Safety of L-serine in ALS
NCT01835782 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Imaging and BioFluid Biomarkers in Amyotrophic Lateral Sclerosis
NCT02559869 ·Status: COMPLETED
-
Biospecimen Biorepository for the Study of ALS, ALS-FTD and Similar Neurodegenerative Disorders
NCT05116943 ·Status: RECRUITING
-
Systems Biology of Amyotrophic Lateral Sclerosis (ALS)
NCT07007390 ·Status: NOT_YET_RECRUITING
-
Amyotrophic Lateral Sclerosis Web Based Patient Care Database: ALSConnection.Org
NCT00302198 ·Status: COMPLETED
-
A Longitudinal Analysis of Biomarkers in Patients With ALS
NCT05309408 ·Status: UNKNOWN
-
Measurement and Impact of Physical Impairment in Amyotrophic Lateral Sclerosis: Use of Digital Technologies - A Precision ALS Project
NCT06820008 ·Status: RECRUITING
-
A Registered Cohort Study on Amyotrophic Lateral Sclerosis
NCT04008329 ·Status: RECRUITING
-
Validation of Biomarkers in Amyotrophic Lateral Sclerosis (ALS)
NCT00677768 ·Status: COMPLETED
-
Amyotrophic Lateral Sclerosis (ALS) Families Project
NCT03865420 ·Status: RECRUITING
-
Amyotrophic Lateral Sclerosis Registry
NCT05892822 ·Status: UNKNOWN
-
Neuroinflammation in Amyotrophic Lateral Sclerosis - Mechanisms and Therapeutic Perspectives: a Translational Pilot Study Among ALS Patients
NCT02424669 ·Status: UNKNOWN ·Phase: NA
-
Clinical Characteristics, Natural History, Health Care Measures, and Genetic Screening in Patients With ALS
NCT05852405 ·Status: COMPLETED
-
COVID-19 Amyotrophic Lateral Sclerosis (ALS) Registry
NCT04559009 ·Status: COMPLETED
-
Clinical Procedures to Support Research in ALS
NCT03489278 ·Status: RECRUITING
-
Cell Signaling, Reinnervation and Metabolism in Kennedy Disease and Amyotrophic Lateral Sclerosis (ALS)
NCT05107349 ·Status: RECRUITING ·Phase: NA
-
Development of Targeted RNA-Seq for Amyotrophic Lateral Sclerosis Diagnosis
NCT06083584 ·Status: RECRUITING
-
ALS/MND Natural History Study Data Repository
NCT05966038 ·Status: RECRUITING
-
DNA, Blood and Skin Cell Repository for Research on ALS and Related Neurodegenerative Disorders at Mayo Clinic Florida
NCT01699451 ·Status: COMPLETED
-
Comprehensive Biomarker Profiling of the IFN-α Pathway in Amyotrophic Lateral Sclerosis Patient Biofluids
NCT07260981 ·Status: COMPLETED
-
Deep Phenotyping in Patients With ALS
NCT02819765 ·Status: COMPLETED
-
Study of Predictive Factors of Progression of Motor Neurone Disease
NCT02360891 ·Status: COMPLETED