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Longitudinal Study of Innate Lymphoid Cells in Peripheral Blood in ALS

NCT03090932 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 66

Last updated 2022-01-12

No results posted yet for this study

Summary

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disorder characterized by progressive muscle weakness and eventual death. Studies demonstrate that the immune system plays a key role in ALS progression; however, the role of the immune system is unclear, as various aspects can play both a beneficial and detrimental role in the disease course. Attempts to universally suppress the immune system in ALS patients have at best had negligible effects on progression or at worst accelerated the disease. Thus, there is a critical need to identify immune cell populations to serve as biomarkers and therapeutic targets.

Conditions

Interventions

OTHER

Blood draw

Research subjects will have two tubes of blood drawn, approximately 20mL.

Sponsors & Collaborators

Principal Investigators

  • Ben Murdock, PhD · University of Michigan

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-01-18
Primary Completion
2020-11-13
Completion
2020-11-13

Countries

  • United States

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03090932 on ClinicalTrials.gov