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PRD-guided Analgesia During FESS for Intraoperative Blood Loss

NCT03417206 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 120

Last updated 2020-10-22

No results posted yet for this study

Summary

The aim of this randomized trial is to assess the utility of Pupillary Dilatation Reflex (PRD) for monitoring pain perception intraoperatively and its influence on intraoperative blood loss, quality of surgical field using Boezaart Bleeding Scale (BBS) in patients undergoing functional sinus surgery (FESS) under total intravenous anaesthesia using propofol or volatile anaesthesia using sevoflurane or desflurane

Conditions

  • Endoscopic Sinus Surgery

Interventions

DRUG

Remifentanil

a rate of infusion will be increased by 50% every 5 minutes until PRD decreases below 5%

DEVICE

pupillary dilatation reflex

PRD value will me measured before the start of FESS after 5 minutes of remifentanyl infusion, when PRD sensitivity \> 5% , infusion of remifentanyl will be increased by 50% until PRD sensitivity \<5% and FESS will be started ; intraoperatively infusion of remifentanyl will be increased by 50% until PRD sensitivity \<5%

Sponsors & Collaborators

  • Medical University of Silesia

    lead OTHER

Principal Investigators

  • Przemysław Jałowiecki, Ph. Dr · Medical University of Silesia

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-09-01
Primary Completion
2023-01-15
Completion
2023-01-15

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03417206 on ClinicalTrials.gov