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Exercise and Weight Control

NCT03413826 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 80

Last updated 2019-12-13

No results posted yet for this study

Summary

The objective of this project is to determine the biological, neurobehavioral, and behavioral compensatory responses to exercise training-induced energy deficits in overweight to obese men and women. Participants will engage in exercise at either 2 days or 6 days per week for 12 weeks and have body composition assessed via DXA before and after the exercise intervention. Accumulated energy balance (weight loss converted to kcal) will be compared to exercise energy expenditure to determine each individual's level of compensation, termed compensation index. Predictors of compensation index that will be assessed will include hunger/satiety hormone concentrations at rest and in response to a meal, reward driven feeding, changes in metabolic rate, and energy intake throughout the intervention. Exercise reinforcement and physical activity will also be assessed as a separate aim to determine if exercise reinforcement can be increased and if this can promote greater habitual physical activity after the intervention has ceased.

Conditions

Interventions

BEHAVIORAL

Exercise

The intervention groups will perform aerobic exercise for 12 weeks, expending 3,000 kcal of energy per week.

Sponsors & Collaborators

  • University of Kentucky

    lead OTHER

Principal Investigators

  • Kyle D Flack, PhD, RD · University of Kentucky

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
FACTORIAL

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-01-04
Primary Completion
2019-08-18
Completion
2019-08-18

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03413826 on ClinicalTrials.gov