Feasibility and Relevance of High-Intensity Functional Training in Patients With First-Episode Psychosis

Summary

The aim of the COPUS study is to investigate, whether it is possible to recruit and retain young people with first-episode psychosis, to an 8 week supervised High-Intensity Functional Training intervention (HIFT) (i.e. COPUS Intervention) and to investigate if oxygen uptake, body composition and physical function improves following participation in the intervention.

Conditions

• Schizophrenia
• Schizotypal Disorder
• First Episode Psychosis
• Psychotic Disorders
• Schizoaffective Disorder

Interventions

OTHER

The COPUS intervention

The COPUS intervention consists of 8 weeks of High-Intensity Functional Training (HIFT). The frequency of the training is 3 sessions per week and the duration is one hour per session. The intervention is group-based and supervised. Each training session includes warm-up (15 min), followed by 30 minutes of HIFT based on a range of varied functional exercises, including elements of strength training and aerobic exercise. The sessions are supervised by a trained physiotherapist and exercise physiologist supported by 2 two trained bachelor students in Sports Science.

OTHER

Usual Care (OPUS treatment)

Usual care include specialised early intervention treatment (OPUS treatment) and consists of three main pillars: modified assertive treatment, family involvement, and social skill training. OPUS treatment is delivered via multidisciplinary teams include psychiatrists, psychologists, nurses, social workers, physiotherapists, and vocational therapists. All team members, except for the psychiatrist, function as case managers. The ratio of patients to case managers must not exceed 12:1.

Sponsors & Collaborators

• University of Copenhagen

  collaborator OTHER

• Mental Health Services in the Capital Region, Denmark

  collaborator OTHER

• Rigshospitalet, Denmark

  lead OTHER

Principal Investigators

• Julie Midtgaard, Ph.D. · The University Hospitals Centre for Health Research (UCSF) / Copenhagen University Hospital (Rigshospitalet)

• Helle Schnor, Ph.D. · Mental health services in the Capital Region of Denmark, Psychiatric Center Glostrup

Study Design

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

NONE

Model

CROSSOVER

Eligibility

Min Age

18 Years

Max Age

35 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2018-01-22

Primary Completion

2018-06-20

Completion

2018-08-01

Countries

• Denmark

Study Locations