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Does VoltagE Guided Additional Ablation Improve Procedural Outcome of Atrial Fibrillation Ablation?

NCT03377751 · Status: TERMINATED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2020-09-09

No results posted yet for this study

Summary

This study is designed to investigate whether pulmonary vein isolation(PVI) plus stepwise additional ablation approach based on the degree of low voltage area versus PVI only can improve procedure outcome in persistent atrial fibrillation(AF) patients.

Conditions

Interventions

PROCEDURE

Voltage-guided substrate homogenization

PVI and additional substrate modification at low voltage areas will be performed according to the following protocol which is based on low voltage area. 1. Proportion of low voltage area to area of left atrium body \<10% : PVI only 2. Proportion of low voltage area to area of left atrium body ≥10% : PVI + substrate homogenization at low voltage areas * Low voltage area will be measured from more than 1000 points of sampled voltage value during sinus rhythm using PentaRay catheter with 3D mapping system of CARTO (Biosense Webster, CA, USA).

PROCEDURE

PVI only group

PVI will be performed in this arm.

PROCEDURE

Additional posterior wall isolation

PVI and additional posterior wall isolation will be performed according to the following protocol which is based on low voltage area. 1. Proportion of low voltage area to area of left atrium body \<10% : PVI only 2. Proportion of low voltage area to area of left atrium body ≥10% : PVI + Posterior wall isolation * Low voltage area will be measured from more than 1000 points of sampled voltage value during sinus rhythm using PentaRay catheter with 3D mapping system of CARTO (Biosense Webster, CA, USA).

Sponsors & Collaborators

  • Korea University Guro Hospital

    lead OTHER

Principal Investigators

  • Hong Euy Lim, MD, Ph.D. · Professor

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
19 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-02-15
Primary Completion
2019-12-15
Completion
2019-12-15

Countries

  • South Korea

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03377751 on ClinicalTrials.gov