Application of the Modified Story Memory Technique (mSMT)© to Aging

NCT03370224 · Status: ENROLLING_BY_INVITATION · Phase: NA · Type: INTERVENTIONAL · Enrollment: 33

Last updated 2025-08-11

No results posted yet for this study

Summary

This study is a double-blind placebo-controlled randomized clinical trial (RCT) to provide Class I evidence in support of or in refute of the efficacy of the modified Story Memory Technique (mSMT) in healthy aging (HA)and in persons with mild cognitive impairment (MCI). Outcomes will be measured through three mechanisms: (1) a traditional neuropsychological evaluation (NPE) (2) an assessment of global functioning (AGF) examining the impact of the treatment on daily activities, and (3) an optional functional magnetic resonance imaging (fMRI) scan.

Conditions

Interventions

BEHAVIORAL

Memory retraining exercises

Memory retraining exercises will be administered on a laptop computer twice a week for 5 weeks (10 training sessions).

BEHAVIORAL

Placebo control memory exercises

Placebo control memory exercises will be administered on a laptop computer twice a week for 5 weeks (10 training sessions).

Sponsors & Collaborators

  • Kessler Foundation

    lead OTHER

Principal Investigators

  • Nancy D Chiaravalloti, PhD · Kessler Foundation

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-11-01
Primary Completion
2026-11-01
Completion
2026-11-01

Countries

  • United States

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03370224 on ClinicalTrials.gov