Application of the Modified Story Memory Technique (mSMT)© to Aging
NCT03370224 · Status: ENROLLING_BY_INVITATION · Phase: NA · Type: INTERVENTIONAL · Enrollment: 33
Last updated 2025-08-11
Summary
This study is a double-blind placebo-controlled randomized clinical trial (RCT) to provide Class I evidence in support of or in refute of the efficacy of the modified Story Memory Technique (mSMT) in healthy aging (HA)and in persons with mild cognitive impairment (MCI). Outcomes will be measured through three mechanisms: (1) a traditional neuropsychological evaluation (NPE) (2) an assessment of global functioning (AGF) examining the impact of the treatment on daily activities, and (3) an optional functional magnetic resonance imaging (fMRI) scan.
Conditions
Interventions
- BEHAVIORAL
-
Memory retraining exercises
Memory retraining exercises will be administered on a laptop computer twice a week for 5 weeks (10 training sessions).
- BEHAVIORAL
-
Placebo control memory exercises
Placebo control memory exercises will be administered on a laptop computer twice a week for 5 weeks (10 training sessions).
Sponsors & Collaborators
-
Kessler Foundation
lead OTHER
Principal Investigators
-
Nancy D Chiaravalloti, PhD · Kessler Foundation
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- TRIPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2017-11-01
- Primary Completion
- 2026-11-01
- Completion
- 2026-11-01
Countries
- United States
Study Locations
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